Rabu, 27 Februari 2013

How is the high density lipoprotein formed? And where specifically?

Q. Where does it come from?

A. It is made mainly near the blood vessels around the body, but the precursors come from the liver.

http://www.nature.com/nrd/journal/v4/n3/fig_tab/nrd1658_F2.html

There are a few sources with handy diagrams
http://cache.eb.com/eb/image?id=96842&rendTypeId=4

How does HDL (High density lipoprotein) reduce the risk of atheroma formation,and Coronary Heart Disease?
Q. and what is the effect of low concentration of HDL inside the blood?

A. HDL carries cholesterol from the body tissues to the liver.

Lower HDL levels result in more cholesterol in blood leading to increased risk of atheroma formation,and Coronary Heart Disease.

What is the role of (HDLs) High Density Lipoproteins in Human Lipoprotein Metabolism?
Q. What is the role of High Density Lipoproteins besides transporting proteins to VLDS (Very Low Density Lipoproteins) and picking up cholesterol from cell membranes and lipoproteins?

A. it takes those vldl and cholesterol to the liver for ketone body formation after beta oxidation of those.




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