Q.
A. Estrogens induce low-density lipoprotein receptor activity and decrease intracellular cholesterol in animals hepatoma cell line Hep G2.
A new reagent effective in inhibiting cholesterol synthesis 75% in human fibroblasts derived from patients suffering from the disease familial hypercholestrolemia is mannose-6-phosphate-low density lipoprotein and is effective in tissue culture test systems at 100 μg/ml after a ten-hour exposure. The broad purpose of this invention is to modify the receptor specificity of a protein so that it will enter cells which were previously impermeable and exert new effects or reverse a pathological condition. Toxins may also be modified in this manner producing cell type specific and tumor suppressive reagents which are effective in a dose range of 0.3-3 μg. The object here is to use the reagent to selectively kill one cell type which is exerting a pathological effect without affecting normal cells. Among others to which this invention is applicable are Man6P-low density lipoprotein, Man6P-ricin, Man6P-Modeccin, anti Thy 1.2 monoclonal antibody-ricin and anti Thy 1.1 monoclonal antibody-ricin.
Take care always!
A new reagent effective in inhibiting cholesterol synthesis 75% in human fibroblasts derived from patients suffering from the disease familial hypercholestrolemia is mannose-6-phosphate-low density lipoprotein and is effective in tissue culture test systems at 100 μg/ml after a ten-hour exposure. The broad purpose of this invention is to modify the receptor specificity of a protein so that it will enter cells which were previously impermeable and exert new effects or reverse a pathological condition. Toxins may also be modified in this manner producing cell type specific and tumor suppressive reagents which are effective in a dose range of 0.3-3 μg. The object here is to use the reagent to selectively kill one cell type which is exerting a pathological effect without affecting normal cells. Among others to which this invention is applicable are Man6P-low density lipoprotein, Man6P-ricin, Man6P-Modeccin, anti Thy 1.2 monoclonal antibody-ricin and anti Thy 1.1 monoclonal antibody-ricin.
Take care always!
How are low density lipoproteins related to health, diet, and cholesterol?
Q. I need the answer by tonight
A. Good cholesterol is high density lipoproteins (HDL) and bad cholesterol is low density lipoproteins (LDL).
Unsaturated fats (most vegetable fats such as nuts, beans, peas and lentils) will increase your HDL level, decrease your LDL level and also reduce your overall cholesterol.
Saturated fats are mostly LDL.
Unsaturated fats (most vegetable fats such as nuts, beans, peas and lentils) will increase your HDL level, decrease your LDL level and also reduce your overall cholesterol.
Saturated fats are mostly LDL.
what is LOW DENSITY LIPOPROTEIN RECEPTOR GENE and what does it do?
Q. i was just wondering what it is.. it doesn't need to be detailed or anything, just a simple english answer
A. I believe that a Low Density Lipoprotein receptor gene is a gene that makes an individual more susceptible to accumulating LDL in their bloodstream. As a side note, LDL is the so called "bad" cholesterol that can stick to fats and cause a blockage in the body.
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