What happens if too much Low density Lipoprotein is in the bloodstream?

Q.

A. They call it "bad cholesterol" for a reason, because it's known that LDL causes vascular inflammation which triggers defense cells to form fibrin and collagen around the lipid deposits creating atheromas. When an atheroma breaks lose, you can get many life threatening conditions, from heart attacks to strokes.

Sometimes if an atheroma doesn't break, it can still cause both before mentioned entities if it fully clogs the blood vessel.

Original Question

Effects of low high density lipoprotein in human body function?

Q.

A. HDL carries the excess cholesterol (LDL) away from the arteries to the liver so that these won't cause atherosclerosis (hardening of the arteries). Low HDL then means a higher risk of heart disease.

Additional
As the for answer from the lady below - try and check out her other posts about cholesterol...

Original Question

where is Low density lipoprotein (LDL) & High density lipoprotein (HDL) synthesized?

Q. Could you also let me know
1. HOW and WHERE they are removed from the bloodstream and
2. Dietary and lifestyle factors that may increase or decrease the amount in the blood (please explain).

I have been researching but I didn't find much.

A. HDL cholesterol "scavenges" your bad cholesterol and helps to eliminate LDL from the body. The only nonpharmacologic way to increase your HDL is to exercise.

Ingesting more soluble fiber lowers your LDL cholesterol because soluble fiber binds bile in the GI tract and it gets eliminated. Bile is synthesized using LDL, so that's why you sometimes see advertising on the side of quaker oats that they can lower your cholesterol. I believe the recommendation is to get 20-30 g of fiber / day.

Original Question

Powered by Yahoo! Answers

Where is Low density lipoprotein (LDL) & High density lipoprotein (HDL) synthesized?

Q. Could you also let me know
1. HOW and WHERE they are removed from the bloodstream and
2. Dietary and lifestyle factors that may increase or decrease the amount in the blood (please explain).

I have been researching but I didn't find much.

A. Mostly the liver makes LDL and HDL which are fats/cholesterol..
You can stop eating cholesterol for the rest of your life and still have high levels. How can this be? For starters, all of your cells can create cholesterol. This is good because every cell in your body needs it to form protective membranes. Your body actually monitors your cells, and if it senses that a cell doesn't have enough cholesterol, it will produce more. Cholesterol also is an essential building block for naturally produced vitamin D and other good stuff, like estrogen and testosterone. But even though every cell can make its own cholesterol, some cells need extra help with their supply. This is where your liver comes in.
Your body, mainly your liver, produces 75 percent of your cholesterol; your small intestine also aids in both the creation and absorption of cholesterol [source: AHA]. The average diet adds another 300 to 500 mg of cholesterol [source: Schafer]. This external cholesterol comes from animal and dairy products. But even if you eat foods without cholesterol, the carbs, fats and proteins all break down eventually and release carbon, which your liver turns into cholesterol.

Original Question

where is Low density lipoprotein (LDL) & High density lipoprotein (HDL) synthesized?

Q. Could you also let me know
1. HOW and WHERE they are removed from the bloodstream and
2. Dietary and lifestyle factors that may increase or decrease the amount in the blood (please explain).

I have been researching but I didn't find much.

A. HDL cholesterol "scavenges" your bad cholesterol and helps to eliminate LDL from the body. The only nonpharmacologic way to increase your HDL is to exercise.

Ingesting more soluble fiber lowers your LDL cholesterol because soluble fiber binds bile in the GI tract and it gets eliminated. Bile is synthesized using LDL, so that's why you sometimes see advertising on the side of quaker oats that they can lower your cholesterol. I believe the recommendation is to get 20-30 g of fiber / day.

Original Question

why would chylomicron, low-density lipoprotein, and high-density lipoprotein form a spherical shape?

Q. not sure if this is important:
chylomicron has 4% phospholipid, 90% triacylglycerol, 5% cholesterol, 1% protein.
low-density lipoprotein has 20% phospholipid, 10% triacylglycerol, 45% cholesterol, 25% protein.
high-density lipoprotein has 30% phospholipid, 5% triacylglycerol, 20% cholesterol, 45% protein.

A. Particles (and systems in general) always follow the "principal of least energy" which reduces the free energy of a system to minimum.

Phospholipids are polar compounds based upon a glycerol backbone. Two fatty acids are attached to the phospholipid at the sn-1, and sn-2 position (end and middle respectively). Both fatty acids are non-polar and hydrophobic (water-hating). The third spot is taken by a polar group at the sn-3 position (e.g. the other end) which is hydrophilic (water loving). In addition to polar amino acids and proteins, the outer side of the lipoprotein particles face the water while the hydrophobic portions point inward, where triglycerides, cholesterol and cholesterol esters are.

The hydrophilic outer portion allows lipoprotein particles to stay suspended in serum and blood. The inner lipid and sterol portion attract each other and form a stable system.

The shape that reduces free energy to a minimum is a sphere so lipoprotein particles assume that shape.

Without the phospholipids and proteins surrounding the water-insoluble portions, the lipid and sterol molecules would simply coalesce, which would result in blobs of fat accumulating in the circulatory system.

Original Question

Powered by Yahoo! Answers

What happens if too much Low density Lipoprotein is in the bloodstream?

Q.

A. They call it "bad cholesterol" for a reason, because it's known that LDL causes vascular inflammation which triggers defense cells to form fibrin and collagen around the lipid deposits creating atheromas. When an atheroma breaks lose, you can get many life threatening conditions, from heart attacks to strokes.

Sometimes if an atheroma doesn't break, it can still cause both before mentioned entities if it fully clogs the blood vessel.

Original Question

Effects of low high density lipoprotein in human body function?

Q.

A. HDL carries the excess cholesterol (LDL) away from the arteries to the liver so that these won't cause atherosclerosis (hardening of the arteries). Low HDL then means a higher risk of heart disease.

Additional
As the for answer from the lady below - try and check out her other posts about cholesterol...

Original Question

where is Low density lipoprotein (LDL) & High density lipoprotein (HDL) synthesized?

Q. Could you also let me know
1. HOW and WHERE they are removed from the bloodstream and
2. Dietary and lifestyle factors that may increase or decrease the amount in the blood (please explain).

I have been researching but I didn't find much.

A. HDL cholesterol "scavenges" your bad cholesterol and helps to eliminate LDL from the body. The only nonpharmacologic way to increase your HDL is to exercise.

Ingesting more soluble fiber lowers your LDL cholesterol because soluble fiber binds bile in the GI tract and it gets eliminated. Bile is synthesized using LDL, so that's why you sometimes see advertising on the side of quaker oats that they can lower your cholesterol. I believe the recommendation is to get 20-30 g of fiber / day.

Original Question

Powered by Yahoo! Answers

Is there a Low density lipoprotein(LDL) and High density lipoprotein (HDL) reader available in the market?

Q.

A. LDL and HDL are determined by Photometry method in a Pathological Laboratory.You are required to give a blood sample for this.
Full Blood profile consists of TC,HDL,TG and LDL.

Original Question

Ldl is 196 triglycerides 154 hdl 31 hdl ratio 8 ldl ratio 6.3 very low density lipoprotein 30.8 my age is 44?

Q.

A. LDL- High LDL level, corresponding to much higher rates for developing symptomatic cardiovascular disease events
Triglyceride- Slightly above normal.
HDL- Low HDL cholesterol, heightened risk for heart disease.
VLDL- slightly above normal.
Risk for cardiac disease is assessed by dividing the total cholesterol level by the HDL level. Target values are <5 for men and <4.4 for women.
Take statin drug in consultation with your doctor.
Also control your cholesterol level by diet and exercise. You may also take omega-3 fatty acid (fish oil).
Adopt DASH diet (Mediterranean diet). Eat a low-cholesterol, low-fat diet, which includes cottage cheese, fat-free milk, fish, vegetables, poultry, and egg whites. Use monounsaturated oils such as olive, peanut, and canola oils or polyunsaturated oils such as corn, safflower, soy, sunflower, cottonseed, and soybean oils. Avoid foods with excess fat in them such as meat (especially liver and fatty meat), egg yolks, whole milk, cream, butter, shortening, pastries, cakes, cookies, gravy, peanut butter, chocolate, olives, potato chips, coconut, cheese (other than cottage cheese), coconut oil, palm oil, and fried foods.
Please note that I am not a medical professional.

Original Question

Do we need both HDL (High-density lipoprotein) and LDL (Low-density lipoprotein)?

Q. If so, then how do vegans exist?

A. The liver and the intestines both form lipoproteins such as HDL, LDL, IDL and VLDL. Levels of each are determined by multiple factors. For example, the fats that are carried by the lipoprotein particles come from food and from fat synthesized by the liver.

Eating foods high in cholesterol actually has little effect of serum cholesterol levels(1). The body has a sensitive feedback mechanism that tightly regulates the production of cholesterol (2). When dietary consumption of cholesterol increases, less is produced by the liver. High levels of insulin increase the synthesis of cholesterol by the liver and also by individual cells in the body.

Fats do have an effect on the levels of HDL, LDL and VLDL. Saturated fats strongly increase HDL and to a lesser estent, LDL. Polyunsaturated fats tend to lower both HDL and LDL. A higher refined carbohydrate intake can strongly increase the serum levels of triglycerides, which can also increase LDL. The liver produces primarily palmitic and palmitoeic acid from carbohydrates. Palmitic acid is also the predominant fatty acid in animal.

Since production of HDL, LDL and triglycerides is mediated by many factors, it is impossible to make many generalizations about the association of dietary fats and carbohydrates and serum cholesterol. Very low carbohydrate diets can result in a more favorable lipid profile than a low fat diet (3). Strict meat eaters can have a fairly low serum choleserol while vegans can have a higher serum cholesterol. People eating a paleolithic diet and a vegan diet can have similarities, in so much that both ways of eating discourage the consumption of vegetable seed oils, refined carbohydrates and favor eating whole foods.

Original Question

Powered by Yahoo! Answers

where is Low density lipoprotein (LDL) & High density lipoprotein (HDL) synthesized?

Q. Could you also let me know
1. HOW and WHERE they are removed from the bloodstream and
2. Dietary and lifestyle factors that may increase or decrease the amount in the blood (please explain).

I have been researching but I didn't find much.

A. HDL cholesterol "scavenges" your bad cholesterol and helps to eliminate LDL from the body. The only nonpharmacologic way to increase your HDL is to exercise.

Ingesting more soluble fiber lowers your LDL cholesterol because soluble fiber binds bile in the GI tract and it gets eliminated. Bile is synthesized using LDL, so that's why you sometimes see advertising on the side of quaker oats that they can lower your cholesterol. I believe the recommendation is to get 20-30 g of fiber / day.

Original Question

why would chylomicron, low-density lipoprotein, and high-density lipoprotein form a spherical shape?

Q. not sure if this is important:
chylomicron has 4% phospholipid, 90% triacylglycerol, 5% cholesterol, 1% protein.
low-density lipoprotein has 20% phospholipid, 10% triacylglycerol, 45% cholesterol, 25% protein.
high-density lipoprotein has 30% phospholipid, 5% triacylglycerol, 20% cholesterol, 45% protein.

A. Particles (and systems in general) always follow the "principal of least energy" which reduces the free energy of a system to minimum.

Phospholipids are polar compounds based upon a glycerol backbone. Two fatty acids are attached to the phospholipid at the sn-1, and sn-2 position (end and middle respectively). Both fatty acids are non-polar and hydrophobic (water-hating). The third spot is taken by a polar group at the sn-3 position (e.g. the other end) which is hydrophilic (water loving). In addition to polar amino acids and proteins, the outer side of the lipoprotein particles face the water while the hydrophobic portions point inward, where triglycerides, cholesterol and cholesterol esters are.

The hydrophilic outer portion allows lipoprotein particles to stay suspended in serum and blood. The inner lipid and sterol portion attract each other and form a stable system.

The shape that reduces free energy to a minimum is a sphere so lipoprotein particles assume that shape.

Without the phospholipids and proteins surrounding the water-insoluble portions, the lipid and sterol molecules would simply coalesce, which would result in blobs of fat accumulating in the circulatory system.

Original Question

Is there a Low density lipoprotein(LDL) and High density lipoprotein (HDL) reader available in the market?

Q.

A. LDL and HDL are determined by Photometry method in a Pathological Laboratory.You are required to give a blood sample for this.
Full Blood profile consists of TC,HDL,TG and LDL.

Original Question

Powered by Yahoo! Answers

what is LOW DENSITY LIPOPROTEIN RECEPTOR GENE and what does it do?

Q. i was just wondering what it is.. it doesn't need to be detailed or anything, just a simple english answer

A. I believe that a Low Density Lipoprotein receptor gene is a gene that makes an individual more susceptible to accumulating LDL in their bloodstream. As a side note, LDL is the so called "bad" cholesterol that can stick to fats and cause a blockage in the body.

Original Question

What happens if too much Low density Lipoprotein is in the bloodstream?

Q.

A. They call it "bad cholesterol" for a reason, because it's known that LDL causes vascular inflammation which triggers defense cells to form fibrin and collagen around the lipid deposits creating atheromas. When an atheroma breaks lose, you can get many life threatening conditions, from heart attacks to strokes.

Sometimes if an atheroma doesn't break, it can still cause both before mentioned entities if it fully clogs the blood vessel.

Original Question

what does low density lipoproteins transport cholestrol to?

Q.

A. LDL transports cholesterol to the vascular tissue. In the vessels, it gets deposited in the atherosclerotic plaques.

Original Question

Powered by Yahoo! Answers

Where is Low density lipoprotein (LDL) & High density lipoprotein (HDL) synthesized?

Q. Could you also let me know
1. HOW and WHERE they are removed from the bloodstream and
2. Dietary and lifestyle factors that may increase or decrease the amount in the blood (please explain).

I have been researching but I didn't find much.

A. Mostly the liver makes LDL and HDL which are fats/cholesterol..
You can stop eating cholesterol for the rest of your life and still have high levels. How can this be? For starters, all of your cells can create cholesterol. This is good because every cell in your body needs it to form protective membranes. Your body actually monitors your cells, and if it senses that a cell doesn't have enough cholesterol, it will produce more. Cholesterol also is an essential building block for naturally produced vitamin D and other good stuff, like estrogen and testosterone. But even though every cell can make its own cholesterol, some cells need extra help with their supply. This is where your liver comes in.
Your body, mainly your liver, produces 75 percent of your cholesterol; your small intestine also aids in both the creation and absorption of cholesterol [source: AHA]. The average diet adds another 300 to 500 mg of cholesterol [source: Schafer]. This external cholesterol comes from animal and dairy products. But even if you eat foods without cholesterol, the carbs, fats and proteins all break down eventually and release carbon, which your liver turns into cholesterol.

Original Question

where is Low density lipoprotein (LDL) & High density lipoprotein (HDL) synthesized?

Q. Could you also let me know
1. HOW and WHERE they are removed from the bloodstream and
2. Dietary and lifestyle factors that may increase or decrease the amount in the blood (please explain).

I have been researching but I didn't find much.

A. HDL cholesterol "scavenges" your bad cholesterol and helps to eliminate LDL from the body. The only nonpharmacologic way to increase your HDL is to exercise.

Ingesting more soluble fiber lowers your LDL cholesterol because soluble fiber binds bile in the GI tract and it gets eliminated. Bile is synthesized using LDL, so that's why you sometimes see advertising on the side of quaker oats that they can lower your cholesterol. I believe the recommendation is to get 20-30 g of fiber / day.

Original Question

why would chylomicron, low-density lipoprotein, and high-density lipoprotein form a spherical shape?

Q. not sure if this is important:
chylomicron has 4% phospholipid, 90% triacylglycerol, 5% cholesterol, 1% protein.
low-density lipoprotein has 20% phospholipid, 10% triacylglycerol, 45% cholesterol, 25% protein.
high-density lipoprotein has 30% phospholipid, 5% triacylglycerol, 20% cholesterol, 45% protein.

A. Particles (and systems in general) always follow the "principal of least energy" which reduces the free energy of a system to minimum.

Phospholipids are polar compounds based upon a glycerol backbone. Two fatty acids are attached to the phospholipid at the sn-1, and sn-2 position (end and middle respectively). Both fatty acids are non-polar and hydrophobic (water-hating). The third spot is taken by a polar group at the sn-3 position (e.g. the other end) which is hydrophilic (water loving). In addition to polar amino acids and proteins, the outer side of the lipoprotein particles face the water while the hydrophobic portions point inward, where triglycerides, cholesterol and cholesterol esters are.

The hydrophilic outer portion allows lipoprotein particles to stay suspended in serum and blood. The inner lipid and sterol portion attract each other and form a stable system.

The shape that reduces free energy to a minimum is a sphere so lipoprotein particles assume that shape.

Without the phospholipids and proteins surrounding the water-insoluble portions, the lipid and sterol molecules would simply coalesce, which would result in blobs of fat accumulating in the circulatory system.

Original Question

Powered by Yahoo! Answers

How to induce Low density lipoprotein or bad cholesterol levels on rabbits please?

Q.

A. Estrogens induce low-density lipoprotein receptor activity and decrease intracellular cholesterol in animals hepatoma cell line Hep G2.

A new reagent effective in inhibiting cholesterol synthesis 75% in human fibroblasts derived from patients suffering from the disease familial hypercholestrolemia is mannose-6-phosphate-low density lipoprotein and is effective in tissue culture test systems at 100 μg/ml after a ten-hour exposure. The broad purpose of this invention is to modify the receptor specificity of a protein so that it will enter cells which were previously impermeable and exert new effects or reverse a pathological condition. Toxins may also be modified in this manner producing cell type specific and tumor suppressive reagents which are effective in a dose range of 0.3-3 μg. The object here is to use the reagent to selectively kill one cell type which is exerting a pathological effect without affecting normal cells. Among others to which this invention is applicable are Man6P-low density lipoprotein, Man6P-ricin, Man6P-Modeccin, anti Thy 1.2 monoclonal antibody-ricin and anti Thy 1.1 monoclonal antibody-ricin.

Take care always!

Original Question

How are low density lipoproteins related to health, diet, and cholesterol?

Q. I need the answer by tonight

A. Good cholesterol is high density lipoproteins (HDL) and bad cholesterol is low density lipoproteins (LDL).

Unsaturated fats (most vegetable fats such as nuts, beans, peas and lentils) will increase your HDL level, decrease your LDL level and also reduce your overall cholesterol.

Saturated fats are mostly LDL.

Original Question

what is LOW DENSITY LIPOPROTEIN RECEPTOR GENE and what does it do?

Q. i was just wondering what it is.. it doesn't need to be detailed or anything, just a simple english answer

A. I believe that a Low Density Lipoprotein receptor gene is a gene that makes an individual more susceptible to accumulating LDL in their bloodstream. As a side note, LDL is the so called "bad" cholesterol that can stick to fats and cause a blockage in the body.

Original Question

Powered by Yahoo! Answers

Do we need both HDL (High-density lipoprotein) and LDL (Low-density lipoprotein)?

Q. If so, then how do vegans exist?

A. The liver and the intestines both form lipoproteins such as HDL, LDL, IDL and VLDL. Levels of each are determined by multiple factors. For example, the fats that are carried by the lipoprotein particles come from food and from fat synthesized by the liver.

Eating foods high in cholesterol actually has little effect of serum cholesterol levels(1). The body has a sensitive feedback mechanism that tightly regulates the production of cholesterol (2). When dietary consumption of cholesterol increases, less is produced by the liver. High levels of insulin increase the synthesis of cholesterol by the liver and also by individual cells in the body.

Fats do have an effect on the levels of HDL, LDL and VLDL. Saturated fats strongly increase HDL and to a lesser estent, LDL. Polyunsaturated fats tend to lower both HDL and LDL. A higher refined carbohydrate intake can strongly increase the serum levels of triglycerides, which can also increase LDL. The liver produces primarily palmitic and palmitoeic acid from carbohydrates. Palmitic acid is also the predominant fatty acid in animal.

Since production of HDL, LDL and triglycerides is mediated by many factors, it is impossible to make many generalizations about the association of dietary fats and carbohydrates and serum cholesterol. Very low carbohydrate diets can result in a more favorable lipid profile than a low fat diet (3). Strict meat eaters can have a fairly low serum choleserol while vegans can have a higher serum cholesterol. People eating a paleolithic diet and a vegan diet can have similarities, in so much that both ways of eating discourage the consumption of vegetable seed oils, refined carbohydrates and favor eating whole foods.

Original Question

What will I do inorder to know my rabbit's high density lipoprotein (HDL) and LOw density lipoprotein (LDL)? ?

Q.

A. Why do you need to know this?

If your bun is acting lethargic, or different from normal, you should get him to a vet. Maybe your vet could do a blood test. But I don't know if that's a standard test for rabbits. I don't think heart disease is very common in rabbits.

Original Question

low-density lipoprotein(LDL) and trygliceride contents are high in cholestrol, precautions and medicines pls.?

Q.

A. Fish balls and turkey genitalias. Also chicken, hot milk, handcuffs, and Macauly Culkin.

Original Question

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How to induce Low density lipoprotein or bad cholesterol levels on rabbits please?

Q.

A. Estrogens induce low-density lipoprotein receptor activity and decrease intracellular cholesterol in animals hepatoma cell line Hep G2.

A new reagent effective in inhibiting cholesterol synthesis 75% in human fibroblasts derived from patients suffering from the disease familial hypercholestrolemia is mannose-6-phosphate-low density lipoprotein and is effective in tissue culture test systems at 100 μg/ml after a ten-hour exposure. The broad purpose of this invention is to modify the receptor specificity of a protein so that it will enter cells which were previously impermeable and exert new effects or reverse a pathological condition. Toxins may also be modified in this manner producing cell type specific and tumor suppressive reagents which are effective in a dose range of 0.3-3 μg. The object here is to use the reagent to selectively kill one cell type which is exerting a pathological effect without affecting normal cells. Among others to which this invention is applicable are Man6P-low density lipoprotein, Man6P-ricin, Man6P-Modeccin, anti Thy 1.2 monoclonal antibody-ricin and anti Thy 1.1 monoclonal antibody-ricin.

Take care always!

Original Question

How are low density lipoproteins related to health, diet, and cholesterol?

Q. I need the answer by tonight

A. Good cholesterol is high density lipoproteins (HDL) and bad cholesterol is low density lipoproteins (LDL).

Unsaturated fats (most vegetable fats such as nuts, beans, peas and lentils) will increase your HDL level, decrease your LDL level and also reduce your overall cholesterol.

Saturated fats are mostly LDL.

Original Question

what is LOW DENSITY LIPOPROTEIN RECEPTOR GENE and what does it do?

Q. i was just wondering what it is.. it doesn't need to be detailed or anything, just a simple english answer

A. I believe that a Low Density Lipoprotein receptor gene is a gene that makes an individual more susceptible to accumulating LDL in their bloodstream. As a side note, LDL is the so called "bad" cholesterol that can stick to fats and cause a blockage in the body.

Original Question

Powered by Yahoo! Answers

why would chylomicron, low-density lipoprotein, and high-density lipoprotein form a spherical shape?

Q. not sure if this is important:
chylomicron has 4% phospholipid, 90% triacylglycerol, 5% cholesterol, 1% protein.
low-density lipoprotein has 20% phospholipid, 10% triacylglycerol, 45% cholesterol, 25% protein.
high-density lipoprotein has 30% phospholipid, 5% triacylglycerol, 20% cholesterol, 45% protein.

A. Particles (and systems in general) always follow the "principal of least energy" which reduces the free energy of a system to minimum.

Phospholipids are polar compounds based upon a glycerol backbone. Two fatty acids are attached to the phospholipid at the sn-1, and sn-2 position (end and middle respectively). Both fatty acids are non-polar and hydrophobic (water-hating). The third spot is taken by a polar group at the sn-3 position (e.g. the other end) which is hydrophilic (water loving). In addition to polar amino acids and proteins, the outer side of the lipoprotein particles face the water while the hydrophobic portions point inward, where triglycerides, cholesterol and cholesterol esters are.

The hydrophilic outer portion allows lipoprotein particles to stay suspended in serum and blood. The inner lipid and sterol portion attract each other and form a stable system.

The shape that reduces free energy to a minimum is a sphere so lipoprotein particles assume that shape.

Without the phospholipids and proteins surrounding the water-insoluble portions, the lipid and sterol molecules would simply coalesce, which would result in blobs of fat accumulating in the circulatory system.

Original Question

Is there a Low density lipoprotein(LDL) and High density lipoprotein (HDL) reader available in the market?

Q.

A. LDL and HDL are determined by Photometry method in a Pathological Laboratory.You are required to give a blood sample for this.
Full Blood profile consists of TC,HDL,TG and LDL.

Original Question

Ldl is 196 triglycerides 154 hdl 31 hdl ratio 8 ldl ratio 6.3 very low density lipoprotein 30.8 my age is 44?

Q.

A. LDL- High LDL level, corresponding to much higher rates for developing symptomatic cardiovascular disease events
Triglyceride- Slightly above normal.
HDL- Low HDL cholesterol, heightened risk for heart disease.
VLDL- slightly above normal.
Risk for cardiac disease is assessed by dividing the total cholesterol level by the HDL level. Target values are <5 for men and <4.4 for women.
Take statin drug in consultation with your doctor.
Also control your cholesterol level by diet and exercise. You may also take omega-3 fatty acid (fish oil).
Adopt DASH diet (Mediterranean diet). Eat a low-cholesterol, low-fat diet, which includes cottage cheese, fat-free milk, fish, vegetables, poultry, and egg whites. Use monounsaturated oils such as olive, peanut, and canola oils or polyunsaturated oils such as corn, safflower, soy, sunflower, cottonseed, and soybean oils. Avoid foods with excess fat in them such as meat (especially liver and fatty meat), egg yolks, whole milk, cream, butter, shortening, pastries, cakes, cookies, gravy, peanut butter, chocolate, olives, potato chips, coconut, cheese (other than cottage cheese), coconut oil, palm oil, and fried foods.
Please note that I am not a medical professional.

Original Question

Powered by Yahoo! Answers

How to induce Low density lipoprotein or bad cholesterol levels on rabbits please?

Q.

A. Estrogens induce low-density lipoprotein receptor activity and decrease intracellular cholesterol in animals hepatoma cell line Hep G2.

A new reagent effective in inhibiting cholesterol synthesis 75% in human fibroblasts derived from patients suffering from the disease familial hypercholestrolemia is mannose-6-phosphate-low density lipoprotein and is effective in tissue culture test systems at 100 μg/ml after a ten-hour exposure. The broad purpose of this invention is to modify the receptor specificity of a protein so that it will enter cells which were previously impermeable and exert new effects or reverse a pathological condition. Toxins may also be modified in this manner producing cell type specific and tumor suppressive reagents which are effective in a dose range of 0.3-3 μg. The object here is to use the reagent to selectively kill one cell type which is exerting a pathological effect without affecting normal cells. Among others to which this invention is applicable are Man6P-low density lipoprotein, Man6P-ricin, Man6P-Modeccin, anti Thy 1.2 monoclonal antibody-ricin and anti Thy 1.1 monoclonal antibody-ricin.

Take care always!

Original Question

How are low density lipoproteins related to health, diet, and cholesterol?

Q. I need the answer by tonight

A. Good cholesterol is high density lipoproteins (HDL) and bad cholesterol is low density lipoproteins (LDL).

Unsaturated fats (most vegetable fats such as nuts, beans, peas and lentils) will increase your HDL level, decrease your LDL level and also reduce your overall cholesterol.

Saturated fats are mostly LDL.

Original Question

what is LOW DENSITY LIPOPROTEIN RECEPTOR GENE and what does it do?

Q. i was just wondering what it is.. it doesn't need to be detailed or anything, just a simple english answer

A. I believe that a Low Density Lipoprotein receptor gene is a gene that makes an individual more susceptible to accumulating LDL in their bloodstream. As a side note, LDL is the so called "bad" cholesterol that can stick to fats and cause a blockage in the body.

Original Question

Powered by Yahoo! Answers

where is Low density lipoprotein (LDL) & High density lipoprotein (HDL) synthesized?

Q. Could you also let me know
1. HOW and WHERE they are removed from the bloodstream and
2. Dietary and lifestyle factors that may increase or decrease the amount in the blood (please explain).

I have been researching but I didn't find much.

A. HDL cholesterol "scavenges" your bad cholesterol and helps to eliminate LDL from the body. The only nonpharmacologic way to increase your HDL is to exercise.

Ingesting more soluble fiber lowers your LDL cholesterol because soluble fiber binds bile in the GI tract and it gets eliminated. Bile is synthesized using LDL, so that's why you sometimes see advertising on the side of quaker oats that they can lower your cholesterol. I believe the recommendation is to get 20-30 g of fiber / day.

Original Question

why would chylomicron, low-density lipoprotein, and high-density lipoprotein form a spherical shape?

Q. not sure if this is important:
chylomicron has 4% phospholipid, 90% triacylglycerol, 5% cholesterol, 1% protein.
low-density lipoprotein has 20% phospholipid, 10% triacylglycerol, 45% cholesterol, 25% protein.
high-density lipoprotein has 30% phospholipid, 5% triacylglycerol, 20% cholesterol, 45% protein.

A. Particles (and systems in general) always follow the "principal of least energy" which reduces the free energy of a system to minimum.

Phospholipids are polar compounds based upon a glycerol backbone. Two fatty acids are attached to the phospholipid at the sn-1, and sn-2 position (end and middle respectively). Both fatty acids are non-polar and hydrophobic (water-hating). The third spot is taken by a polar group at the sn-3 position (e.g. the other end) which is hydrophilic (water loving). In addition to polar amino acids and proteins, the outer side of the lipoprotein particles face the water while the hydrophobic portions point inward, where triglycerides, cholesterol and cholesterol esters are.

The hydrophilic outer portion allows lipoprotein particles to stay suspended in serum and blood. The inner lipid and sterol portion attract each other and form a stable system.

The shape that reduces free energy to a minimum is a sphere so lipoprotein particles assume that shape.

Without the phospholipids and proteins surrounding the water-insoluble portions, the lipid and sterol molecules would simply coalesce, which would result in blobs of fat accumulating in the circulatory system.

Original Question

Is there a Low density lipoprotein(LDL) and High density lipoprotein (HDL) reader available in the market?

Q.

A. LDL and HDL are determined by Photometry method in a Pathological Laboratory.You are required to give a blood sample for this.
Full Blood profile consists of TC,HDL,TG and LDL.

Original Question

Powered by Yahoo! Answers

How to induce Low density lipoprotein or bad cholesterol levels on rabbits please?

Q.

A. Estrogens induce low-density lipoprotein receptor activity and decrease intracellular cholesterol in animals hepatoma cell line Hep G2.

A new reagent effective in inhibiting cholesterol synthesis 75% in human fibroblasts derived from patients suffering from the disease familial hypercholestrolemia is mannose-6-phosphate-low density lipoprotein and is effective in tissue culture test systems at 100 μg/ml after a ten-hour exposure. The broad purpose of this invention is to modify the receptor specificity of a protein so that it will enter cells which were previously impermeable and exert new effects or reverse a pathological condition. Toxins may also be modified in this manner producing cell type specific and tumor suppressive reagents which are effective in a dose range of 0.3-3 μg. The object here is to use the reagent to selectively kill one cell type which is exerting a pathological effect without affecting normal cells. Among others to which this invention is applicable are Man6P-low density lipoprotein, Man6P-ricin, Man6P-Modeccin, anti Thy 1.2 monoclonal antibody-ricin and anti Thy 1.1 monoclonal antibody-ricin.

Take care always!

Original Question

How are low density lipoproteins related to health, diet, and cholesterol?

Q. I need the answer by tonight

A. Good cholesterol is high density lipoproteins (HDL) and bad cholesterol is low density lipoproteins (LDL).

Unsaturated fats (most vegetable fats such as nuts, beans, peas and lentils) will increase your HDL level, decrease your LDL level and also reduce your overall cholesterol.

Saturated fats are mostly LDL.

Original Question

what is LOW DENSITY LIPOPROTEIN RECEPTOR GENE and what does it do?

Q. i was just wondering what it is.. it doesn't need to be detailed or anything, just a simple english answer

A. I believe that a Low Density Lipoprotein receptor gene is a gene that makes an individual more susceptible to accumulating LDL in their bloodstream. As a side note, LDL is the so called "bad" cholesterol that can stick to fats and cause a blockage in the body.

Original Question

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where is Low density lipoprotein (LDL) & High density lipoprotein (HDL) synthesized?

Q. Could you also let me know
1. HOW and WHERE they are removed from the bloodstream and
2. Dietary and lifestyle factors that may increase or decrease the amount in the blood (please explain).

I have been researching but I didn't find much.

A. HDL cholesterol "scavenges" your bad cholesterol and helps to eliminate LDL from the body. The only nonpharmacologic way to increase your HDL is to exercise.

Ingesting more soluble fiber lowers your LDL cholesterol because soluble fiber binds bile in the GI tract and it gets eliminated. Bile is synthesized using LDL, so that's why you sometimes see advertising on the side of quaker oats that they can lower your cholesterol. I believe the recommendation is to get 20-30 g of fiber / day.

Original Question

why would chylomicron, low-density lipoprotein, and high-density lipoprotein form a spherical shape?

Q. not sure if this is important:
chylomicron has 4% phospholipid, 90% triacylglycerol, 5% cholesterol, 1% protein.
low-density lipoprotein has 20% phospholipid, 10% triacylglycerol, 45% cholesterol, 25% protein.
high-density lipoprotein has 30% phospholipid, 5% triacylglycerol, 20% cholesterol, 45% protein.

A. Particles (and systems in general) always follow the "principal of least energy" which reduces the free energy of a system to minimum.

Phospholipids are polar compounds based upon a glycerol backbone. Two fatty acids are attached to the phospholipid at the sn-1, and sn-2 position (end and middle respectively). Both fatty acids are non-polar and hydrophobic (water-hating). The third spot is taken by a polar group at the sn-3 position (e.g. the other end) which is hydrophilic (water loving). In addition to polar amino acids and proteins, the outer side of the lipoprotein particles face the water while the hydrophobic portions point inward, where triglycerides, cholesterol and cholesterol esters are.

The hydrophilic outer portion allows lipoprotein particles to stay suspended in serum and blood. The inner lipid and sterol portion attract each other and form a stable system.

The shape that reduces free energy to a minimum is a sphere so lipoprotein particles assume that shape.

Without the phospholipids and proteins surrounding the water-insoluble portions, the lipid and sterol molecules would simply coalesce, which would result in blobs of fat accumulating in the circulatory system.

Original Question

Is there a Low density lipoprotein(LDL) and High density lipoprotein (HDL) reader available in the market?

Q.

A. LDL and HDL are determined by Photometry method in a Pathological Laboratory.You are required to give a blood sample for this.
Full Blood profile consists of TC,HDL,TG and LDL.

Original Question

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where is Low density lipoprotein (LDL) & High density lipoprotein (HDL) synthesized?

Q. Could you also let me know
1. HOW and WHERE they are removed from the bloodstream and
2. Dietary and lifestyle factors that may increase or decrease the amount in the blood (please explain).

I have been researching but I didn't find much.

A. HDL cholesterol "scavenges" your bad cholesterol and helps to eliminate LDL from the body. The only nonpharmacologic way to increase your HDL is to exercise.

Ingesting more soluble fiber lowers your LDL cholesterol because soluble fiber binds bile in the GI tract and it gets eliminated. Bile is synthesized using LDL, so that's why you sometimes see advertising on the side of quaker oats that they can lower your cholesterol. I believe the recommendation is to get 20-30 g of fiber / day.

Original Question

why would chylomicron, low-density lipoprotein, and high-density lipoprotein form a spherical shape?

Q. not sure if this is important:
chylomicron has 4% phospholipid, 90% triacylglycerol, 5% cholesterol, 1% protein.
low-density lipoprotein has 20% phospholipid, 10% triacylglycerol, 45% cholesterol, 25% protein.
high-density lipoprotein has 30% phospholipid, 5% triacylglycerol, 20% cholesterol, 45% protein.

A. Particles (and systems in general) always follow the "principal of least energy" which reduces the free energy of a system to minimum.

Phospholipids are polar compounds based upon a glycerol backbone. Two fatty acids are attached to the phospholipid at the sn-1, and sn-2 position (end and middle respectively). Both fatty acids are non-polar and hydrophobic (water-hating). The third spot is taken by a polar group at the sn-3 position (e.g. the other end) which is hydrophilic (water loving). In addition to polar amino acids and proteins, the outer side of the lipoprotein particles face the water while the hydrophobic portions point inward, where triglycerides, cholesterol and cholesterol esters are.

The hydrophilic outer portion allows lipoprotein particles to stay suspended in serum and blood. The inner lipid and sterol portion attract each other and form a stable system.

The shape that reduces free energy to a minimum is a sphere so lipoprotein particles assume that shape.

Without the phospholipids and proteins surrounding the water-insoluble portions, the lipid and sterol molecules would simply coalesce, which would result in blobs of fat accumulating in the circulatory system.

Original Question

Is there a Low density lipoprotein(LDL) and High density lipoprotein (HDL) reader available in the market?

Q.

A. LDL and HDL are determined by Photometry method in a Pathological Laboratory.You are required to give a blood sample for this.
Full Blood profile consists of TC,HDL,TG and LDL.

Original Question

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Effects of low high density lipoprotein in human body function?

Q.

A. HDL carries the excess cholesterol (LDL) away from the arteries to the liver so that these won't cause atherosclerosis (hardening of the arteries). Low HDL then means a higher risk of heart disease.

Additional
As the for answer from the lady below - try and check out her other posts about cholesterol...

Original Question

Where is Low density lipoprotein (LDL) & High density lipoprotein (HDL) synthesized?

Q. Could you also let me know
1. HOW and WHERE they are removed from the bloodstream and
2. Dietary and lifestyle factors that may increase or decrease the amount in the blood (please explain).

I have been researching but I didn't find much.

A. Mostly the liver makes LDL and HDL which are fats/cholesterol..
You can stop eating cholesterol for the rest of your life and still have high levels. How can this be? For starters, all of your cells can create cholesterol. This is good because every cell in your body needs it to form protective membranes. Your body actually monitors your cells, and if it senses that a cell doesn't have enough cholesterol, it will produce more. Cholesterol also is an essential building block for naturally produced vitamin D and other good stuff, like estrogen and testosterone. But even though every cell can make its own cholesterol, some cells need extra help with their supply. This is where your liver comes in.
Your body, mainly your liver, produces 75 percent of your cholesterol; your small intestine also aids in both the creation and absorption of cholesterol [source: AHA]. The average diet adds another 300 to 500 mg of cholesterol [source: Schafer]. This external cholesterol comes from animal and dairy products. But even if you eat foods without cholesterol, the carbs, fats and proteins all break down eventually and release carbon, which your liver turns into cholesterol.

Original Question

where is Low density lipoprotein (LDL) & High density lipoprotein (HDL) synthesized?

Q. Could you also let me know
1. HOW and WHERE they are removed from the bloodstream and
2. Dietary and lifestyle factors that may increase or decrease the amount in the blood (please explain).

I have been researching but I didn't find much.

A. HDL cholesterol "scavenges" your bad cholesterol and helps to eliminate LDL from the body. The only nonpharmacologic way to increase your HDL is to exercise.

Ingesting more soluble fiber lowers your LDL cholesterol because soluble fiber binds bile in the GI tract and it gets eliminated. Bile is synthesized using LDL, so that's why you sometimes see advertising on the side of quaker oats that they can lower your cholesterol. I believe the recommendation is to get 20-30 g of fiber / day.

Original Question

Powered by Yahoo! Answers

How are low density lipoproteins related to health, diet, and cholesterol?

Q. I need the answer by tonight

A. Good cholesterol is high density lipoproteins (HDL) and bad cholesterol is low density lipoproteins (LDL).

Unsaturated fats (most vegetable fats such as nuts, beans, peas and lentils) will increase your HDL level, decrease your LDL level and also reduce your overall cholesterol.

Saturated fats are mostly LDL.

Original Question

what is LOW DENSITY LIPOPROTEIN RECEPTOR GENE and what does it do?

Q. i was just wondering what it is.. it doesn't need to be detailed or anything, just a simple english answer

A. I believe that a Low Density Lipoprotein receptor gene is a gene that makes an individual more susceptible to accumulating LDL in their bloodstream. As a side note, LDL is the so called "bad" cholesterol that can stick to fats and cause a blockage in the body.

Original Question

What happens if too much Low density Lipoprotein is in the bloodstream?

Q.

A. They call it "bad cholesterol" for a reason, because it's known that LDL causes vascular inflammation which triggers defense cells to form fibrin and collagen around the lipid deposits creating atheromas. When an atheroma breaks lose, you can get many life threatening conditions, from heart attacks to strokes.

Sometimes if an atheroma doesn't break, it can still cause both before mentioned entities if it fully clogs the blood vessel.

Original Question

Powered by Yahoo! Answers

How are low density lipoproteins related to health, diet, and cholesterol?

Q. I need the answer by tonight

A. Good cholesterol is high density lipoproteins (HDL) and bad cholesterol is low density lipoproteins (LDL).

Unsaturated fats (most vegetable fats such as nuts, beans, peas and lentils) will increase your HDL level, decrease your LDL level and also reduce your overall cholesterol.

Saturated fats are mostly LDL.

Original Question

what is LOW DENSITY LIPOPROTEIN RECEPTOR GENE and what does it do?

Q. i was just wondering what it is.. it doesn't need to be detailed or anything, just a simple english answer

A. I believe that a Low Density Lipoprotein receptor gene is a gene that makes an individual more susceptible to accumulating LDL in their bloodstream. As a side note, LDL is the so called "bad" cholesterol that can stick to fats and cause a blockage in the body.

Original Question

What happens if too much Low density Lipoprotein is in the bloodstream?

Q.

A. They call it "bad cholesterol" for a reason, because it's known that LDL causes vascular inflammation which triggers defense cells to form fibrin and collagen around the lipid deposits creating atheromas. When an atheroma breaks lose, you can get many life threatening conditions, from heart attacks to strokes.

Sometimes if an atheroma doesn't break, it can still cause both before mentioned entities if it fully clogs the blood vessel.

Original Question

Powered by Yahoo! Answers

What happens if too much Low density Lipoprotein is in the bloodstream?

Q.

A. They call it "bad cholesterol" for a reason, because it's known that LDL causes vascular inflammation which triggers defense cells to form fibrin and collagen around the lipid deposits creating atheromas. When an atheroma breaks lose, you can get many life threatening conditions, from heart attacks to strokes.

Sometimes if an atheroma doesn't break, it can still cause both before mentioned entities if it fully clogs the blood vessel.

Original Question

Effects of low high density lipoprotein in human body function?

Q.

A. HDL carries the excess cholesterol (LDL) away from the arteries to the liver so that these won't cause atherosclerosis (hardening of the arteries). Low HDL then means a higher risk of heart disease.

Additional
As the for answer from the lady below - try and check out her other posts about cholesterol...

Original Question

Where is Low density lipoprotein (LDL) & High density lipoprotein (HDL) synthesized?

Q. Could you also let me know
1. HOW and WHERE they are removed from the bloodstream and
2. Dietary and lifestyle factors that may increase or decrease the amount in the blood (please explain).

I have been researching but I didn't find much.

A. Mostly the liver makes LDL and HDL which are fats/cholesterol..
You can stop eating cholesterol for the rest of your life and still have high levels. How can this be? For starters, all of your cells can create cholesterol. This is good because every cell in your body needs it to form protective membranes. Your body actually monitors your cells, and if it senses that a cell doesn't have enough cholesterol, it will produce more. Cholesterol also is an essential building block for naturally produced vitamin D and other good stuff, like estrogen and testosterone. But even though every cell can make its own cholesterol, some cells need extra help with their supply. This is where your liver comes in.
Your body, mainly your liver, produces 75 percent of your cholesterol; your small intestine also aids in both the creation and absorption of cholesterol [source: AHA]. The average diet adds another 300 to 500 mg of cholesterol [source: Schafer]. This external cholesterol comes from animal and dairy products. But even if you eat foods without cholesterol, the carbs, fats and proteins all break down eventually and release carbon, which your liver turns into cholesterol.

Original Question

Powered by Yahoo! Answers