Sabtu, 01 Juni 2013

If someone has hyperlipidemia, how soon after a blood draw can you see the lipids in their blood?

Q. I'm doing a case study on a patient with hyperlipidemia, among other things, and I found a photo of a vial of blood showing the lipids sitting at the top of the vial. It states that this photo was taken 4 hrs after the blood was drawn & I'm wondering if it has to sit for that long to be visible?

A. It is correct as soon as the blood starts to separate and settle or clot and separate, which begins immediately in around a half an hour you have pretty good separation, but we don't spin the blood down for 30 minutes (not when you need to get a result out in an hour)-5-10 minutes is more like it.

Do i have hyperlipidemia and obesity?
Q. so it wasnt long ago when i got blood out of me. i got a letter from the mail today saying im referred to a cardiology and nutritionist, and the near middle it saids this:
"Diagnosis: Obesity, Hyperlipidemia" , So do i have hyperlipidemia and obesity. Best Answer Get Max Points. Thank you for responding.
So by you saying yes i do have it but it can be diagnosis.

A. Hyperlipidemia is just a fancy name for high cholesterol. So, you are apparently overweight and have high cholesterol - these two things usually occur together and both are usually diet-related.

How does hypertention, hyperlipidemia, and smoking, participate in the pathophysiology of atherosclerosis?
Q.

A. http://en.wikipedia.org/wiki/Atherosclerosis
Cigarette-endothelial dysfunction and a relatively hypercoagulable state
hypertention-morphologic alterations of the arterial intima and functional alterations of the endothelium
hyperlipidemia- Endothelial injury
Bottom line- All risk factors cause endothelial dysfunction which is the earliest manifestation of atherosclerosis




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Jumat, 31 Mei 2013

What can I do as a woman after menapause do to improve on my Cholesterol and Triglyceride blood results?

Q. In April 2006 my blood work showed: Cholesterol 167.6; Triglyceride 220.4 and HDL 38.1. I am talking Lipitor during both of these blood tests.
In October 2006 my blook work showed: Cholesterol 211.1; Triglyceride 143.7 and HDL 48.5.
I listed the HDL because I was afraid the Lipitor was effecting my Good Cholestrol count.
I'm looking for someone that can tell me why my cholestrol went up this time and triglycerides went down and what is my next course of action.

A. Eat cabbage, oatmeal, apples, etc. for soluble fiber and of course some type of exercise.

Also, here's some all-natural supplements that are very effective.

OmegaGuard: reduces the risk of heart disease/stroke, lowers triglycerides and cholesterol

Soluble Fiber (e.g. Fiber Plan): prevents fat absorption; reduces stress on heart by minimizing fat accumulation

Lecithin: converts serum cholesterol to good HDL

CoQHeart: Reduces LDL oxidation

Garlic Complex: prevents clotting; dilates small blood vessels; dissolves fatty deposits & thins blood

Hope this is useful and feel free to contact me with questions.

What determines whether a triglyceride is saturated or unsaturated?
Q. Is it the bonds?

A. A trigylceride (fat) is basically a glycerol molecule joined to three fatty acid molecules. The fatty acid molecules are often called "fatty acid chains" or "fatty acid tails".

Triglyceride structure:
http://www.indiana.edu/~oso/Fat/FatImg/triglyceride.jpg

If a triglyceride contains fatty acid tails with only single bonds in their structure, it is said to be saturated (saturated with hydrogens - it contains the maximum no. of C-H bonds).

If a triglyceride contains one or more fatty acid tails which contain at least one double bond in their structure, it is said to be unsaturated.

Here is a pic which shows the difference between saturated and unsaturated fats:
http://www.realfitnessblog.com/wp-content/uploads/2008/11/fat_f2.jpg

As the pic above shows, saturated fats are usually straight, so the molecules can pack together tightly, which is why saturated fats are solids at room temp. The double bonds in the structure of unsaturated fats makes kinks in the chain preventing the neat packing together of these molecules, so most unsaturated fats are liquids at room temp.

What is the function of Triglyceride and Phospholipid?
Q. Also, what are some examples of nucleic acids besides DNA and RNA?

Thanks!

A. Triglycerides and Phospholipids are present in the Plasma Membrane of the cell to make each cell regionally distinct from one another.




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High cholesterol, when do you have to start taking medication?

Q. My hubby's reading today was
HDL - 61
LDL - 167
Trigy - 89
Cholesterol ratio - 4.0
Total cholesterol - 246
Fasting glucose - 93
Blood pressure 138/80

Does this look normal or should he be on medication due to the high LDL? At what readings should a person be diagnosed with medication? Appreciate your kind replies.
Thanks so much for your kind reply, Pauline.

A. Its not bad... and definitely not bad enough to take medication. I am not a doctor but I am a natural health nut who has family with high cholesterol and I watch this stuff closely.

Medication is an absolute last resort. What you will usually get is Lipitor and one your on that, its pretty much forever.... its tailored that way.

The best way to lower cholesterol is change your diet.. figure out what foods created it in the first place (chips, mashed potatoes and gravies, red meat, bacon.....its pretty obvious what does unless you just naturally produce cholesterol in your bloodstream) and eliminate them. A good routine is always eat a whole grain breakfast within 30 minutes of waking in the morning (even if you dont eat breakfast, its the most important meal and your cholesterol will lower just by doing that in most cases)as well drink 8 to 16 oz of water, clean fresh water, not tap. Then eat fibre througout the day at least every two hours.. carrots, apples, fibre bar whatever.... drink lots of water (this is the nectar of life, it has been neglected for years but science is realizing its really important to keep cells in your body working properly). There is also another thing you can do... drink an ounce of apple-cider vinegar every morning..... it cleans the arteries.... and get a multi-vitamin that contains B50 and niacin.... these also help keep the arteries clean and feed the heart which is what we worry about with high cholesterol. I know this is long but I just wanted to help... I dont promote taking any pills for quick fix... because its not good for your body to take pills.. then you have to take other pills to offset side effects and the next thing you know you have 20 pills to take every day.. the body isnt designed to filter pills..... which is why I believe people are sick in this day and age.

Good Luck

How is cholesterol calculated and can you have too much good cholesterol?
Q. I went to the doctor and my cholesterol was 246 which isn't so good but my good cholesterol was 65, which she said is great. Is the LDL what's remaining after the good cholesterol is subtracted from the total? Can you have too much HDL?

A. HDL are "high-density lipoproteins" which is fancy doctor talk for cells that are high in protein, low in fat/cholesterol. This is preferred, as this is what "feeds" the body with growth proteins. Proteins power "cell" creation and repair (only). Things like muscle, skin, hair, etc...anything that grows or requires frequent repair benefit from higher counts of HDL. HDL's increase in demand with more activity. Specifically 'cardio' (meaning heart) workouts. You really can't have "too much" HDL's because if the body doesnt need the level of proteins in the blood sugar, it simply release it as it passes through the kidneys. We pee out excess proteins. They do NOT convert to bodyfat like some bodybuilders like to beleive.

LDLs are of course "Low density", meaning low protein high fat. LDL's partially provide energy to "active" muscles. The cells are often "coated" with saturated fats. As these move around the body feeding active muscles, they 'bump along' the artery walls, the leave little "skid marks" so to speak. These marks build up to become plaque, and can cause heart decrease. Reducing LDL's to under 200, (or 150 even better) would be good advice but often requires medication, diet modification, AND more physical activity.

How much cholesterol would be in a ostrich egg?
Q. Actually, you can eat ostrich eggs. Eggs are eggs. Just to let you know.

A. An ostrich egg is supposed to be equal to 2 dozen chicken eggs. That would mean 2520 grams of cholesterol.




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Kamis, 30 Mei 2013

What does it mean if my triglyceride is low?

Q. I am a young adult and recently had a blood test taken. My triglyceride level was a low 26, the norm is 35-160. What does this mean and what are the risks of having a low amount? Also, what is the function of triglyceride and how can I raise it?

A. Triglycerides are the form that dietary fat takes in your blood. You do not want to raise your trigylceride level because it can lead to heart disease and other health complications. Its best to keep it low.

Can triglyceride levels in dogs increase from the chewing/eating of rawhide?
Q. I have increased the amount of rawhide chews I give to my Beagle, and coincidentally, her triglycerides soared. Is there any connection between the two? Otherwise, she is fed Nutro Ultra for Seniors dry mixed with a little bit of canned and water for a sauce. She is not fed fats, and has a healthy diet of fruits and veggies for snacks.

A. most raw-hides are deep fried or oven basted with chicken fat as dripping, so are just full of fat. You can get healthier ones if you search, but they cost more. Most people recommend the nylon bones, but I have heard if they are too small the dogs can swallow them whole, then you will need an operation.

I give my dogs a small healthy meaty bone to chew daily, its part of their breakfast calorie, is natural and much lower in fat.

Why is a triglyceride considered hydrophobic when it has a glycerol molecule which is hydrophilic?
Q. also- can everything be categorized as hydrophilic and hydrophobic?

lastly- if the outside of our membranes is hydrophilic wouldn't we dissolve in water?

A. The hydroxyl group of glycerol joins in an ester linkage with the carboxyl group on the lipid leaving a hydrophilic compound.

Not all compounds are one or the other some are amphiphilic with a polar hydrophilic end and a nonpolar lipophilic hydrocarbon end like the phospholipids in cell membranes.




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How to induce Low density lipoprotein or bad cholesterol levels on rabbits please?

Q.

A. Estrogens induce low-density lipoprotein receptor activity and decrease intracellular cholesterol in animals hepatoma cell line Hep G2.

A new reagent effective in inhibiting cholesterol synthesis 75% in human fibroblasts derived from patients suffering from the disease familial hypercholestrolemia is mannose-6-phosphate-low density lipoprotein and is effective in tissue culture test systems at 100 μg/ml after a ten-hour exposure. The broad purpose of this invention is to modify the receptor specificity of a protein so that it will enter cells which were previously impermeable and exert new effects or reverse a pathological condition. Toxins may also be modified in this manner producing cell type specific and tumor suppressive reagents which are effective in a dose range of 0.3-3 μg. The object here is to use the reagent to selectively kill one cell type which is exerting a pathological effect without affecting normal cells. Among others to which this invention is applicable are Man6P-low density lipoprotein, Man6P-ricin, Man6P-Modeccin, anti Thy 1.2 monoclonal antibody-ricin and anti Thy 1.1 monoclonal antibody-ricin.

Take care always!

How are low density lipoproteins related to health, diet, and cholesterol?
Q. I need the answer by tonight

A. Good cholesterol is high density lipoproteins (HDL) and bad cholesterol is low density lipoproteins (LDL).

Unsaturated fats (most vegetable fats such as nuts, beans, peas and lentils) will increase your HDL level, decrease your LDL level and also reduce your overall cholesterol.

Saturated fats are mostly LDL.

what is LOW DENSITY LIPOPROTEIN RECEPTOR GENE and what does it do?
Q. i was just wondering what it is.. it doesn't need to be detailed or anything, just a simple english answer

A. I believe that a Low Density Lipoprotein receptor gene is a gene that makes an individual more susceptible to accumulating LDL in their bloodstream. As a side note, LDL is the so called "bad" cholesterol that can stick to fats and cause a blockage in the body.




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Rabu, 29 Mei 2013

Do we need both HDL (High-density lipoprotein) and LDL (Low-density lipoprotein)?

Q. If so, then how do vegans exist?

A. The liver and the intestines both form lipoproteins such as HDL, LDL, IDL and VLDL. Levels of each are determined by multiple factors. For example, the fats that are carried by the lipoprotein particles come from food and from fat synthesized by the liver.

Eating foods high in cholesterol actually has little effect of serum cholesterol levels(1). The body has a sensitive feedback mechanism that tightly regulates the production of cholesterol (2). When dietary consumption of cholesterol increases, less is produced by the liver. High levels of insulin increase the synthesis of cholesterol by the liver and also by individual cells in the body.

Fats do have an effect on the levels of HDL, LDL and VLDL. Saturated fats strongly increase HDL and to a lesser estent, LDL. Polyunsaturated fats tend to lower both HDL and LDL. A higher refined carbohydrate intake can strongly increase the serum levels of triglycerides, which can also increase LDL. The liver produces primarily palmitic and palmitoeic acid from carbohydrates. Palmitic acid is also the predominant fatty acid in animal.

Since production of HDL, LDL and triglycerides is mediated by many factors, it is impossible to make many generalizations about the association of dietary fats and carbohydrates and serum cholesterol. Very low carbohydrate diets can result in a more favorable lipid profile than a low fat diet (3). Strict meat eaters can have a fairly low serum choleserol while vegans can have a higher serum cholesterol. People eating a paleolithic diet and a vegan diet can have similarities, in so much that both ways of eating discourage the consumption of vegetable seed oils, refined carbohydrates and favor eating whole foods.

What will I do inorder to know my rabbit's high density lipoprotein (HDL) and LOw density lipoprotein (LDL)? ?
Q.

A. Why do you need to know this?

If your bun is acting lethargic, or different from normal, you should get him to a vet. Maybe your vet could do a blood test. But I don't know if that's a standard test for rabbits. I don't think heart disease is very common in rabbits.

low-density lipoprotein(LDL) and trygliceride contents are high in cholestrol, precautions and medicines pls.?
Q.

A. Fish balls and turkey genitalias. Also chicken, hot milk, handcuffs, and Macauly Culkin.




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Of the following cell types, the greatest concentration of high-density lipoprotein (HDLs) would be associated?

Q. Of the following cell types, the greatest concentration of high-density lipoprotein (HDLs) would be associated with ________ cells
A) skin
B) muscle
C) connective tissue
D) blood
E) liver

A. Though these proteins that transport cholesterol are in the blood...
the liver is the one that makes this cholesterol, if it isn't obtained
from the foods we eat.

The LDL, which is considered the bad cholesterol...is the lipo
protein that transport cholesterol out from the liver to the cells
and is known to clog the arteries.

The HDL is the lipo protein that transports
cholesterol back to the liver...so since it is the HDL....
then I believe the answer would be the liver (E).

This seems kind of tricky...considering the cholesterol
is transported in the blood...so it might also be D) Blood
since blood tests are taken to determine how much
HDL and LDL are present.

Hope this has been of some help. Best wishes

Where is Low density lipoprotein (LDL) & High density lipoprotein (HDL) synthesized?
Q. Could you also let me know
1. HOW and WHERE they are removed from the bloodstream and
2. Dietary and lifestyle factors that may increase or decrease the amount in the blood (please explain).

I have been researching but I didn't find much.

A. Mostly the liver makes LDL and HDL which are fats/cholesterol..
You can stop eating cholesterol for the rest of your life and still have high levels. How can this be? For starters, all of your cells can create cholesterol. This is good because every cell in your body needs it to form protective membranes. Your body actually monitors your cells, and if it senses that a cell doesn't have enough cholesterol, it will produce more. Cholesterol also is an essential building block for naturally produced vitamin D and other good stuff, like estrogen and testosterone. But even though every cell can make its own cholesterol, some cells need extra help with their supply. This is where your liver comes in.
Your body, mainly your liver, produces 75 percent of your cholesterol; your small intestine also aids in both the creation and absorption of cholesterol [source: AHA]. The average diet adds another 300 to 500 mg of cholesterol [source: Schafer]. This external cholesterol comes from animal and dairy products. But even if you eat foods without cholesterol, the carbs, fats and proteins all break down eventually and release carbon, which your liver turns into cholesterol.

where is Low density lipoprotein (LDL) & High density lipoprotein (HDL) synthesized?
Q. Could you also let me know
1. HOW and WHERE they are removed from the bloodstream and
2. Dietary and lifestyle factors that may increase or decrease the amount in the blood (please explain).

I have been researching but I didn't find much.

A. HDL cholesterol "scavenges" your bad cholesterol and helps to eliminate LDL from the body. The only nonpharmacologic way to increase your HDL is to exercise.

Ingesting more soluble fiber lowers your LDL cholesterol because soluble fiber binds bile in the GI tract and it gets eliminated. Bile is synthesized using LDL, so that's why you sometimes see advertising on the side of quaker oats that they can lower your cholesterol. I believe the recommendation is to get 20-30 g of fiber / day.




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